Hyderabad-based cardiologist Dr Syed Akram Ali recently shared a worrying case of a 37-year-old who, despite running 5 km daily, eating no junk, sleeping on time, and having no vices, needed two stent placements in his heart. โA healthy man with no junk food, ran 5 km had 2 stents.
He ran 5 km every morning. He avoided junk food.
He didnโt smoke, didnโt drink, slept on time, did everything โright. โ Yet last month, this 37-year-old Hyderabad man landed in the cath lab with chest pressure and left arm heavinessโฆAn angiography showed two major blockages.
He needed two stents,โ Dr Ali noted in an Instagram post. According to the expert, the real hidden causes that most people never check are genetic/family risk (the silent killer).
โIf your father/uncle had early heart issues, your risk is 2โ3ร higher โ even if youโre fit, lean, and active. โ Another reason could be lipoprotein(a) โ โthe most dangerous cholesterol (not checked in routine tests)โ.
โNormal lipid profile is NOT enough. Lp(a) is purely genetic.
High levels clog arteries even if LDL is โnormal,โ added Dr Ali. DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to.
Always consult your health practitioner before starting any routine. High stress + corporate lifestyle is another reason.
โ5 km running is not equal to stress management. Stress increases adrenaline, blood pressure, inflammation and causes microplaque formation. โ Inflammation (CRP) is also to blame.
โMany โfitโ people have hidden inflammation, which leads to faster artery damage. Not measured in regular checkups,โ said Dr Ali. Poor sleep quality like sleeping 6 hours with screens till midnight = metabolic strain.
โRaises cortisol, thickens blood, increases plaque instability,โ said Dr Ali. Hereโs what you should consider (Photo: Getty Images/Thinkstock) Hereโs what you should consider (Photo: Getty Images/Thinkstock) Misleading fitness beliefs are to be blamed, too.
โRunning keeps you fit. It doesnโt guarantee clean arteries.
Heart disease = genes + lifestyle + inflammation + stress + sleep + lipoprotein,โ said Dr Ali. Story continues below this ad Dr Ali listed the tests every Indian above 25 must do: Lipoprotein(a) HS-CRP (inflammation marker) ApoB HbA1c Fasting insulin VitD Homocysteine TMT(If symptoms) Coronary calcium score (above 35 years) To verify, we consulted with Dr Parin Sangoi, consultant, interventional cardiologist, Wockhardt Hospitals, Mumbai Central, who told indianexpress.
com that physical fitness does not guarantee good arterial health. โA person may have good endurance but still develop plaque in the coronary arteries. Genetic factors, such as family history or high Lipoprotein(a) levels, can speed up plaque formation even when cholesterol levels seem normal,โ said Dr Sangoi.
Several hidden factors often go unchecked. Lipoprotein(a), a purely genetic cholesterol particle, can silently clog arteries even when routine cholesterol levels are normal.
Dr Sangoi concurred that lipoprotein(a), or Lp(a), is a cholesterol particle determined by genetics that does not appear on routine lipid tests. โHigh levels significantly raise the risk of early heart attacks and serious artery blockages. Because it is inherited, even young, lean individuals can be affected without any warning signs,โ said Dr Sangoi.
Story continues below this ad Chronic stress, especially in corporate lifestyles, increases blood pressure, inflammation, and plaque formation, which exercise alone cannot undo, said Dr Rahul Gupta, director and cardiologist at Gleneagles Hospital, Parel. โPoor sleep quality, constant screen exposure, and untreated inflammation further weaken artery health.
Many โfitโ individuals also have high CRP levels, insulin resistance, or elevated homocysteine, none of which show up in basic tests. This is why a normal lipid profile or regular running is not enough,โ said Dr Gupta.
View this post on Instagram A post shared by DrSyedakram Ali (@dr. syedakramali) Markers such as HS-CRP for inflammation, ApoB, HbA1c, fasting insulin, and homocysteine provide a more comprehensive view of cardiovascular risk.
In certain individuals, a coronary calcium score can identify early plaque even before symptoms appear, said Dr Sangoi. Emphasising that heart disease results from genes, inflammation, stress, sleep, and metabolic health combined, Dr Gupta said early, advanced testing and preventive evaluation are essential to protect the heart truly.
DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.


